PS3201 Family Studies Essay Example | Topics and Well Written Essays - 3500 words

PS3201 Family Studies - Essay Example The element of a family constitutes a husband, children, and a wife who reside under the same roof. The interaction among the above elements shapes or defines the behavior that a person who demonstrate in the society. However, the description is limited to what many people believe to constitute nuclear family. In some traditional settings especially in Africa, family would constitute members of nuclear family and members from the extended wing (Strong, et.al. 2010:420). The extended elements are aunts, uncles, and grandparents. This paper will examine a family in the modern era. Family setting depends with cultural practices observed by a given community. Communities across the globe demonstrate their cultural heritage through the association, which they project through their families. Traditions in Nigeria regarded a family as institution that was center to human existence i.e. sustainability of human race depended on the constitution of new families (Rotimi, 2005:8). The culture propagated by people started from a family. The regard that the community gave to family was an institution just like other social institutions where people demonstrated adherence to order or law. The values set in the family included how to bring up a child, how children would relate with community members, courtship, rules of descent, ownership of property among other taboos. The taboos observed by a family had moral consequence to individuals who went against the norms. People believed in practices stipulated in cultural norms. Men had cultural responsibility of heading their f amilies (The Fellows’ Forum, 2005:13). Rules set by communities gave an opportunity to men to have as men women as possible as long as the man was able to cater for their needs. The traditional setting recognized the existence of the relatives and the role in the family (Omoera, 2010:78). For example, brothers in law

Statement of Purpose Essay Example for Free

Statement of Purpose Essay Firstly I would like to introduce myself as an undergraduate student of the bachelor of engineering program From the M.S.Ramaiah institute of technology, one of the most prestigious institutions of the Bangalore U university . I have completed my course of engineering in the field of Industrial Engineering’, which was for a period of four years. I graduated in the first class with distinction. I was ranked among the top five in the class. During these four years of my undergraduate course, I gained in-depth understanding of the various techniques involved in problem solving, mainly to cater to the services of the industries. Manufacturing Processes, Operations Research, Industrial Management, Quantitative techniques were the other subjects which enabled me to blend the required action whenever an problem was posed to me. Behavioral Science was the most interesting subject which I mastered during this four year peroid.This subject provided me with valuable information which helped me to develop leadership skills .The factor of empathy really coerced me to instigate leadership skills.. Since computers have become inseparable part of INDUSTRIAL ENGINEERING I deemed it fit to learn more about computers and I am presently doing my course in C,C++. I have worked on software packages like MS Project,LINDO, LOTUS 123.To meet my B.E. Degree requirement ,I executed a project titled REDUCTION OF LEAD CYCLE FOR MANUFACTURE OF STEAM TURBINES under the expert guidance of N.V.R.Naidu and this project was presented in the O.R. Society of India. The main aim of the project was to reduce the lead cycle of manufacture of a particular class of turbine so as to reduce the inventory costs and enable the industry to forecast accurately for the period ahead. The techniques involved LINE OF BALANCE METHOD for scheduling and Controlling and Post college, I AM presently working in KIRLOSKAR ELECTRIC COMPANY WHERE IN I am going through a rigorous training program which will be completed very shortly. The undergraduate course as well as my training at KIRLOSKAR ELECTRIC COMPANY has provided me with a strong base for further growth in any of my desired fields. I would like to delve deeper into the fields of my choice and their technical aspects completely. I hope to acquire the requisite professional skills and develop a thorough understanding in these following areas. I wish to contribute towards these areas and indulge in research which ultimately should have a meaningful contribution to science and technology. I AM confident that my academic capability and analytical skills coupled with my perseverance and single minded devotion will see me through to this goal. To this end, the first step is a sound graduate study. I have chosen the graduate program to further my interests. It is my belief that knowledge gained has to be shared. I believe that imparting knowledge is an enjoyable and satisfying experience. I have enjoyed giving ideas, lectures and making presentations on technical/non technical topics at college and at the workplace. Hence, I am eager to obtain An assistantship.Consequently,I understand that the choice of the University is of paramount importance. After perusing your brochures and consulting my professors, I reached the conclusion that the with its reputed faculty, excellent facilities and tradition of academic excellence will be the ideal place to work towards the fulfillment o my goal. Moreover, I am confident that the wholesome education that I will receive at the will stand me in good stead throughout my career. Thanking you,

Endosymbiotic Theory of Eukaryotic Cell Development

Endosymbiotic Theory of Eukaryotic Cell Development Abstract The defining feature of eukaryotic cells is that they contain membrane-bound organelles and a true nucleus. The endosymbiotic theory is based upon the idea that eukaryotic cells evolved in steps beginning with the stable incorporation of chemo-organotrophic and phototrophic symbionts from the domain bacteria. This essay reviewed the evidence that supports this theory. After investigating the molecular, physiological and morphological evidence, it is almost certain that chloroplasts and mitochondria are from the domain bacteria, and that many of the genes required for the survival of these organelles are contained within the nuclear DNA of the eukaryotic cell rather than the organelles own independent DNA. It is for this reason that I believe that endosymbiosis was the process whereby eukaryotes began to form and evolve. It was found that the genome of a protozoan, Reclinomonas, contained all the protein-coding found in sequenced mitochondrial genomes, providing support for the specul ative process of endosymbiotic gene transfer. The hydrogen hypothesis seems to be the most likely scenario for the formation of eukaryotes, which explains the need for compartmentalisation with increasing host genome size to improve efficiency of function throughout the cell, and the chimeric nature of eukaryotes. Introduction Based upon data collected from slow decaying radioactive isotopes, Earth is thought to have formed approximately 4.55 billion years ago. From this time of origin, a continual process of geological and physical change has occurred, which created conditions leading to the origin of life about 4 billion years ago. Life is thought to have undergone the process of evolution, defined as DNA sequence change and the inheritance of that change, often under the selective pressures of a changing environment. (1) Microfossil evidence suggests that unicellular eukaryotes arose on Earth approximately 2 billion years ago, after the development of an oxic environment and the invention of respiratory metabolism in cyanobacteria. This timing infers that the availability of oxygen was a large influence on the biological evolution that led to the emergence of Eukarya. (1) The defining characteristic of eukaryotes is the presence of a well-defined nucleus within each cell. (2) Typical eukaryotic cells contain a membrane bound nucleus and organelles enclosed by an outer plasma membrane; these organelles are organised into compartmentalised structures which have their own function(s) within the cell, often working together with other organelles to complete vital biological processes. This compartmentation in cells is essential in organisms as it allows differing compositions of nutrients to exist inside each compartment as opposed to outside, creating perfect conditions for biochemical reactions to occur.(3) The differences between eukaryotes and prokaryotes are shown in Table 1: Mitochondria are membrane-bound organelles found in the cytoplasm of most eukaryotic cells and are most concentrated in cells associated with active processes, such as muscle cells which constantly require energy for muscle contraction. The two surrounding membranes that encompass a mitochondrion differ in function and composition, creating distinct compartments within the organelle. The outer membrane is regular in appearance and composed of proteins and lipids, in roughly equal measure, whilst the outer membrane contains porin proteins rendering it more permeable. The inner membrane is only freely permeable to oxygen, water and carbon dioxide; it contains many infoldings, or cristae, that protrude into the central matrix space, significantly increasing the surface area and giving it an irregular shape. As can be seen in Figure 1, mitochondria contain ribosomes and have their own genetic material, mitochondrial DNA (mtDNA), separate from the nuclear DNA. (4) Mitochondria are the principle sites of ATP production- in a process known as oxidative phosphorylation. Products of the Krebs cycle, NADH + H+ and FADH2, are carried forward to the electron transport chain (ETC) and are oxidised to NAD+ and FAD, releasing hydrogen atoms. These hydrogen atoms split to produce protons and electrons, and the electrons are passed down the ETC between electron carriers, losing energy at each level. This energy is utilised by pumping the protons into the intermembranal space causing an electrochemical gradient between the intermembranal space and the mitochondrial matrix. The protons diffuse down the electrochemical gradient through specific channels on the stalked particles of the cristae, where ATPsynthase located at the stalked particles, supplies electrical potential energy to convert ADP and inorganic phosphate to ATP. In mammalian cells, enzymes in the inner mitochondrial membrane and central matrix space carry out the terminal stages of glucose and fatty acid oxidation in the process of ATP synthesis. Mitochondria also play an important role in the regulation of ionised calcium concentration within cells, largely due to their ability to accumulate substantial amounts of calcium. (3)(5) Chloroplasts are membrane-bound organelles found within photosynthetic eukaryotes. Chloroplasts are surrounded by a double membrane, the outer membrane being regular in appearance whilst the inner membrane contains infoldings to form an interconnected system of disc-shaped sacs named thylakoids. These are often arranged in to stacks called grana. Enclosed within the inner membrane of the chloroplast is a fluid-filled region called the stroma, containing water and the enzymes necessary for the light-independent reactions (the Calvin cycle) in photosynthesis. The thylakoid membrane is the site of the light dependent reactions in photosynthesis, and contains photosynthetic pigments (such as chlorophyll and carotenoids) and electron transport chains. Chloroplasts, like mitochondria, contain ribosomes and their own independent DNA (ctDNA), which is central to the theory of endosymbiosis. The structure of a typical chloroplast is shown by Figure 2: Radiant energy is trapped by photosynthetic pigments and used to excite electrons in order to produce ATP by photophosphorylation. The light dependent reactions occur in the thylakoid membrane (Photosystem II or P680) and ultimately, these reactions produce the ATP and NADPH required for photosynthesis to continue in the stroma (where Photosystem I or P700 is located). A series of light independent reactions occur within the stroma producing carbohydrates from carbon dioxide and water using ATP and NADPH. The most supported hypothesis (put forward by Lynn Margulis) for the origin of the eukaryotic cell is that of endosymbiosis which is suitably named as symbiosis occurs when two different species benefit from living and working together. When one organism actually lives inside the other its called endosymbiosis.'(6) The endosymbiosis hypothesis states that the modern, or organelle-containing eukaryotic cell evolved in steps through the stable incorporation of chemo-organotrophic and phototrophic symbionts from the domain Bacteria. In other words, chloroplasts and mitochondria of modern-day eukaryotes arose from the stable incorporation into a second type of cell of a chemoorganotrophic bacterium, which underwent facultative aerobic respiration, and a cyanobacterium, which carried out oxygenic photosynthesis. The beneficial association between the engulfed prokaryote and eukaryote would have given the eukaryote an advantage over neighbouring cells, and the theory is that the prokaryote and eukaryote lost the ability to live independently. (1) Oxygen was an important factor in endosymbiosis and in the rise of the eukaryotic cell through its production in photosynthesis by the ancestor of the chloroplast and its consumption in energy-producing metabolic processes by the ancestor of the mitochondrion. It is worth noting that eukaryotes underwent rapid evolution, most probably due to their ability to exploit sunlight for energy and the greater yields of energy released by aerobic respiration. Support for the endosymbiosis hypothesis can be found in the physiology and metabolism of mitochondria and chloroplasts, as well as the structure and sequence of their genomes.(1) Similarities between modern-day chloroplasts, mitochondria, and prokaryotes relative to eukaryotes are shown in table 2: Molecular Evidence When Margulis proposed the endosymbiotic theory, she predicted that if the organelles really were prokaryotic symbionts, they would contain their own independent DNA. This was proven to be the case in the 1980s for mitochondria and chloroplasts.(7)Furthermore, mitochondrial DNA (mtDNA) was found to have a proportionally higher ratio of guanine-cytosine base pairs than in eukaryotic nuclear DNA, as found in bacteria. These findings are significant as they strongly suggest that mitochondria and chloroplasts are of prokaryotic origin and nature, supporting the possibility that the eukaryotic cell evolved from the stable incorporation of symbionts from the domain Bacteria. Another striking similarity between mitochondria and bacteria is that they both contain 70S ribosomes and contain a comparable order of genes encoding ribosomal proteins a shown in Figure 4: It is only fair that the molecular problems associated with the endosymbiosis hypothesis that have been put forward are considered. Firstly, mitochondria and chloroplasts can only arise from pre-existing mitochondria and chloroplasts, having lost many essential genes needed for survival. It has been suggested that this is because of the large timespan that the mitochondria/chloroplasts have co-existed. During this time, systems and genes that were no longer needed were either simply deleted or transferred into the host genome. Hence, mitochondria and chloroplasts have lost the ability to live independently over time. This supports the endosymbiotic theory as it provides a reason as to why the ancestors of the chloroplasts and mitochondria were able to survive independently whilst chloroplast and mitochondria are unable to do so now. The study of mitochondrial genomes so far has suggested that mitochondrial genomes actually encode less than 70 of the proteins that mitochondria need to function; most being encoded by the nuclear genome and targeted to mitochondria using protein import machinery that is specific to this organelle.(7) It has been found that the genome of Reclinomonas contains all the protein-coding genes found in all the sequenced mitochondrial genomes: (8) The importance of Figure 5 is that it shows that the mitochondrial genome no longer contains many of the protein-coding genes, and hence, mitochondria are no longer able to live independently. The mitochondrial endosymbiont is believed to have belonged to the proteobacteria since several genes and proteins still encoded by the mitochondrial genome branch in molecular trees among homologues from this group. Interestingly, mitochondrial proteins such as the 60- and 70-kDa heat shock proteins (Hsp60, Hsp70), also branch amongst proteobacterial homologues, but the genes are encoded by the host nuclear genome.(9) This can be explained by a theory called endosymbiotic gene transfer which states that during the course of mitochondrial genome reduction, genes were transferred from the endosymbionts genome to the hosts chromosomes, but the encoded proteins were reimported into the organelle where they originally functioned. (7) This theory is central to the endosymbiotic theory, as it explain s the inability of chloroplasts and mitochondria to live independently even though these organelles are believed to have originated from the domain Bacteria. It is also believed that this gene transfer has provided an essential way in which mitochondrial or chloroplast activity can be regulated. The studies of protists raise  the possibility that mitochondria originated at essentially  the same time as the nuclear component of the eukaryotic cell  rather than in a separate, subsequent event. (10) T This would fit in with the hydrogen hypothesis as described later. A further problem to consider is the extent to which genes were transferred to the cell nucleus. Why did some genes remain in the cytoplasmic organelles? This question has been addressed by the Co-location for  Redox  Regulation (CoRR) hypothesis, which states that the location of  genetic information  in  cytoplasmic  organelles  permits regulation of its expression by the reduction-oxidation  (redox) state of its  gene products. Therefore, evolution by natural selection would have favoured mitochondrial or chloroplast cells that had deleted or transferred some genes to the host genome but had kept those that were still beneficial in the regulation of the organelles activity. (11) Physiological Evidence Evidence for the endosymbiosis theory can be found in the physiology of mitochondria and chloroplasts. For example, both mitochondria and chloroplasts have their own protein-synthesising machinery which closely resembles that of Bacteria rather than that of Eukaryotes. Ribosome function in mitochondria and chloroplasts are inhibited by the same antibiotics that inhibit ribosome function in free-living bacteria. Hence, it is no surprise that both these organelles contain 70S ribosomes typical of prokaryotic cells, and show 16S ribosomal RNA gene sequences, a characteristic of certain Bacteria such as Escherichia coli.(1) For example, human mitochondrial ribosomes can be affected by chloramphenicol (an antibiotic used to inhibit protein synthesis), further evidence that mitochondria are likely to be of bacterial origin. Chloramphenicol is a relatively simple molecule containing a nitrobenzene ring responsible for some of the toxicity problems associated with the drug: Chloramphenicol inhibits protein synthesis due to its high affinity for the large (50S) ribosomal subunit, which when bound to chloramphenicol, blocks the action of peptidyl transferase, preventing peptide bond synthesis. It has also been discovered that chloramphenicol prevents the maturation of the 30S ribosomal subunits, decreasing the number of competent subunits and significantly decreasing the proportion of mitochondrial ribonucleoprotein present as monomers. (12) Also, the antibiotic rifampicin which inhibits the RNA polymerase of Bacteria has been found to inhibit the RNA polymerase within bacteria. Proteins of chloroplast or mitochondrion origin, like bacteria, always use N-formylmethionine as their initiating amino acid of their transcript.(13) Mitochondria replicate, like bacteria, only by the process of binary fission inferring that mitochondria did indeed originate from prokaryotes. The completion of the genome sequence of the cyanobacterium Synechocystis, has provided e vidence for the origin of chloroplast translocation apparatus. Just as the endosymbiosis theory predicts, analysis of this sequence showed that three key translocation components within chloroplasts, Toc75, Tic22 and Tic20, evolved from existing proteins within the cyanobacterial genome.(14)Mitochondria and chloroplasts have remarkably similar mechanisms by which ATP is produced. These ATP-generating pathways often include electron transport chains and proton pumps, similar to that found in prokaryotic energy production mechanisms. One of the most recent problems with the endosymbiosis theory is found within the physiology of mitochondria. Mounting evidence suggests that key components of the mitochondrial transcription and replication apparatus are derived from the T-odd lineage of  bacteriophage  rather than from an ÃŽÂ ±-Proteobacterium, as the endosymbiont hypothesis would predict.'(15) It has been discovered that three of the essential elements of the replication and transcription apparatus; the RNA polymerase, the replicative primase-helicase and the DNA polymerase do not resemble those of eubacteria as predicted by the symbiosis theory, but instead appears to resemble proteins encoded by T-odd bacteriophages. However, this does not disprove the theory of endosymbiosis as it is conceivable that numerous mitochondrial genes were acquired together from an ancestor of T-odd phage early in the formation of the eukaryotic cell, at the time when the mitochondrial symbiont was incorporated. (15) Morphological Evidence Another characteristic that further supports the hypothesis is that mitochondria and chloroplasts contain small amounts of DNA that is different from that of the cell nucleus which is arranged in a covalently closed, circular structure, with no associated histones, typical of Bacteria. Mitochondria are surrounded by two membranes, separated by the inter-membranal space and each with a different composition. Mitochondrial membranes more closely resemble membranes found in Gram-negative bacteria in terms of lipid composition than eukaryotic membranes. (16) The inner-membrane infoldings in the mitochondria lends more credibility to the endosymbiosis theory as the cristae are adaptations that increase the surface area of oxidative enzymes, evolutionary analogues to the mesosomal membranes of many prokaryotes (16)Further evidence that mitochondria and chloroplasts are of a prokaryotic origin is the lack of cholesterol in their membranes. This is significant because it is an essential stru ctural component in many eukaryotic membranes, mainly in mammalian cell membrane, but it almost completely absent amongst prokaryotes. Another problem is that recent genetic analysis of small eukaryotes that lack many characteristics that are associated with eukaryotic cells, most importantly mitochondria, show that they all still retain genes involved in the synthesis of mitochondrial proteins. In 1983, the taxon Archezoa was proposed to unite this group of odd eukaryotes, and the belief was that these cells had diverged from other eukaryotes before these characteristics evolved and hence represented primitive eukaryotic lineages. Before the recent genetic breakthrough that shows that these eukaryotes contain genes involved in mitochondrial protein synthesis, molecular work supported their primitive status, as they consistently fell deep into the branches of eukaryotic trees. This recent genetic analysis implies that all these eukaryotes once had mitochondria, suggesting that they evolved after the mitochondrial symbiosis. There is also the question of how the eukaryotic cell arose, including the nature and propert ies of the cell that acquired mitochondria and later chloroplasts, and how the nuclear membrane was formed which touches upon the compatmentalisation within cells and its importance in the functioning of the eukaryotic cell. (7) Formation of the eukaryotic cell There have been two hypotheses put forward to explain how the eukaryotic cell arose. One states that eukaryotes started as a nucleus-bearing lineage that later acquired the bacterial ancestor of the mitochondrion and the cyanobacterial ancestor of the chloroplast by the process of endosymbiosis. This nucleated line then diverged into the lineages giving rise to animals and plants. It is thought that the nucleus arose spontaneously in an early cell. One possible cause for the spontaneous formation of the nucleus is that it arose in response to the increasing genome size of early eukaryotes. (1) The second hypothesis, also known as the hydrogen hypothesis, states that the bacterial ancestor of the mitochondrion was taken up by a member of the Archaea via endosymbiosis, and from this association, the nucleus later emerged, followed by a later acquisition of the cyanobacterial ancestor of the chloroplast. The main difference between these two hypotheses is the position of the mitochondrion relative to the formation of the nucleus in time and hence on the universal phylogenetic tree. The hydrogen hypothesis put forward by William F. Martin and Miklos Muller in 1998, proposes that the eukaryotic cell arose from a symbiotic association of an anaerobic, hydrogen dependent, autotrophic archaebacterium (the host) with a hydrogen producing, oxygen consuming eubacterium (the symbiont), which released molecular hydrogen as a waste product of anaerobic heterotrophic metabolism. (17) The dependence of the host upon the molecular hydrogen as an energy source, produced as a waste product b y the symbiont is thought to be what lead to the association. In this scenario, the nucleus arose following the formation of this stable association between these two kinds of cells, and genes involved in lipid synthesis were transferred from the symbiont to the host chromosome. This may have lead to the synthesis of bacterial (symbiont) lipids by the host, eventually leading to the creation of an internal membrane system, the endoplasmic reticulum and the early stages of a eukaryotic nucleus. As the size of the host genome increased with time, changes were made to maximise the efficiency of replication and gene expression via the process of evolution. Hence, over time, this kind of cell compartmentalised and sequestered the genetic coding information within a protected membrane away from the cytoplasm. The formation of a mitochondrion-containing nucleated cell line was complete, which then later acquired chloroplasts by endosymbiosis. The hydrogen hypothesis has explains the observ ation that eukaryotes are of chimeric nature, containing attributes of both Bacteria and Archaea. (1) Conclusions In summary, molecular, physiological and morphological evidence can be found to support the endosymbiosis theory put forward by Lynn Margulis. Most compelling of which is the numerous similarities between organelles such as chloroplasts and mitochondria with prokaryotes, coupled with the inability of the organelles to live independently despite having their own independent DNA due to most of the genes required for the survival of the organelle being stored in the nuclear DNA of the host. The importance of this should not be underestimated, as it does all but prove that the ancestors of mitochondria and chloroplasts were of a prokaryotic origin and thus were once able to live independently. Therefore, this does lend credibility to the endosymbiosis theory as the symbionts that were allegedly incorporated were likely to have been from the domain bacteria, and that something must have occurred which stopped the symbionts being able to live independently, an event which many scientists n ow believe to be the process of endosymbiotic gene transfer. The hydrogen hypothesis appears to be the likely scenario for how the eukaryotic cell evolved, as it explains the formation of the nucleus as being a response to the growing size of the nuclear genome of the host, which would have maximised efficiency of gene expression. Endosymbiosis also explains why the eukaryotic cell appears to be of a chimeric nature; containing attributes of Archaea (e.g. similar transcription and translation apparatus) and Bacteria (e.g. contain same type of lipids).

Euthanasia Essay example -- essays research papers fc

LEGALIZATION OF PHYSICIAN-ASSISTED SUICIDE I. Beginning   Ã‚  Ã‚  Ã‚  Ã‚  A. â€Å" Whose life is it, anyway?† These were the words of the late Sue Rodrigues, a   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  high-profile, terminally-ill resident of British Columbia, Canada, who suffered   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  from ALS (Lou Gehrig’s Disease). She was helped to commit suicide by a   Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  physician in violation of Canadian Law.   Ã‚  Ã‚  Ã‚  Ã‚  B. Most people in North America die what may be called a bad death. One study   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  found that â€Å" More often than not, patients died in pain, their desires concerning   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  treatment neglected, after spending 10 days or more in the intensive care unit. †   Ã‚  Ã‚  Ã‚  Ã‚  C. I believe that because so many people are dying so painfully, there are more reasons   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  or physician-assisted suicide to be legal than not. II. Middle   Ã‚  Ã‚  Ã‚  Ã‚  A. Physician-Assisted Suicide is:   Ã‚  Ã‚  Ã‚  Ã‚   1. a form of euthanasia in which a doctor gives access to a person the means to kill him   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  or herself   Ã‚  Ã‚  Ã‚  Ã‚  B. A Physician is:   Ã‚  Ã‚  Ã‚  Ã‚   1. a doctor   Ã‚  Ã‚  Ã‚  Ã‚  C. Steps in the process and methods of Physician-Assisted Suicide   Ã‚  Ã‚  Ã‚  Ã‚   1. There are three ways:   Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  a. One method is Dr. Jack Kevorkian’s â€Å"Suicide Machine. In this process,   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  the patient must first activate it by pushing a button. Then, three solutions   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  are injected in order; first, a harmless saline, then, a sleep-inducing   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  ative, and finally the lethal drug.   &n... ...Home Page. 5 May 1998   Ã‚  Ã‚  Ã‚  Ã‚  . Remmelink Report, The. 1990-1991. . Robinson, Bruce A. ReligiousTolerance.org Home Page.1 Jan. 2000   Ã‚  Ã‚  Ã‚  Ã‚  . â€Å"Saga of Dr. Jack, The.† About.com. 21 Mar. 2000   Ã‚  Ã‚  Ã‚  Ã‚  . â€Å"Self-Deliverance: New Technology.† ERGO! . 1 Dec. 1999.   Ã‚  Ã‚  Ã‚  Ã‚  . Simon, Melissa. Home Page . Walker, Richard. A Right To Die?. New York, New York: Franklin Watts, 1996. Weiss, Ann E. Bioethics: Dilemmas in Modern Medicine. Hillside, NJ: Enslow Publishers, Inc. â€Å"When Death is Our Physician.† Ultimate, Pro-Life Resource List. Dec. 1999   Ã‚  Ã‚  Ã‚  Ã‚  . Yount, Lisa. Issues in Biomedical Ethics. San Diego, California: Lucent Books, 1998.

Health and Sanitation in Victorian London :: European Europe History

Health and Sanitation in Victorian London Diet, Health, and Sanitation in Victorian England are so interrelated that it is difficult to examine one without being led to another. A.S. Wohl sums it up when he states: "It is rather commonplace of modern medical opinion that nutrition plays a crucial role in the body's ability to resist disease and the experience of the World Health Organization indicates that where sanitary conditions are rudimentary and disease is endemic (that is, where nineteenth-century conditions prevail, so to speak) diet may be the crucial factor in infection" (Wohl 56). However, there was often a vicious cycle at work in these trying times and it is difficult to point to the root causes of some of the contagion that infected people. Also there were various philosophies, some not as instructive as others, being practiced in the early part of the nineteenth century that tried to explain sanitation problems and poverty. When can see how pervasive this problem was as it made its way into much of the literat ure at the time. Its representation was rather grim. Works such as Charles Dickens's Oliver Twist and Elizabeth Gaskell's Mary Barton represent the harsh reality of these conditions. While much of the investigation into the sanitary conditions of the times focused on the working classes, disease and poor sanitation also found their way into the higher classes of society. However, there often remained the prevailing stigma that a dirty body and poor sanitation was the result of some sort of moral failing. Graham Benton puts his finger on this view rather succinctly in his piece which recently appeared in the Dickens Quarterly: "'And Dying Thus Around Us Every Day': Pathology, Ontology and the Discourse of the Diseased Body. A Study of Illness and Contagion In Bleak House." Benton suggests that: "although contagious disease refuses to recognize boundaries of class, it has become aligned with the disenfranchised and disavowed segments of society, and, more significantly, disease became emblematic of other unrelated but equally horrific social ills" (69). Whatever the motivations to end the plight of contagion and unsanitary conditions might have been at the time; it is fair to say that when the spread of disease crossed the invisible boundaries of class that people were spurred into action, albeit not as quickly as they should have. While poor drainage and waste disposal procedures can be seen as a direct result of fever and epidemic; it is important first to look at the dietary practices of the working classes which would greatly contribute to their squalid living conditions.

Amadou Ham Pate Ba

Amadou Ham pate Ba (1901-1991), Malian ethnologist, narrator and author, played an important role in introducing the world to African oral heritage, especially the folktales of West Africa. The man known as the â€Å"living Memory of Africa† he liked to say he was â€Å"one of the eldest sons of the century,† was one of the major intellectual literary figures of the 20th century. The saying with which he will always be associated for (his often quoted statement), that â€Å"In Africa when an old man dies, a library has burned down† has become so famous that it is sometimes used as an African proverb.He was commenting on the loss of African oral heritage, in praise of both old age and oral tradition, which contributes to the historical components of humanities memory. â€Å"The folktale is a key source of oral tradition, as are other forms of narrative and rituals that are considered essential components of cultural anthropology and ethnology†. (folkculture . org) There is a certain characteristic and significance of indigenous knowledge, especially in Africa. Indigenous knowledge has been defined as the local knowledge. Knowledge that is unique to a given culture or society.The expressions traditional local and indigenous knowledge, are used in the literature inter-changeably, is learned through repetition which aids in its retention and reinforcement. Agricultural or desert-based societies slowly created communities that were mostly self- contained and based on self-help. Their approach to problem solving was through ambulated individual or communal experiences and knowledge derived from trial and error. This aggregated validated knowledge improved and increases in time but remained mostly unrecorded. Even in the present information age, agricultural and desert-based communities, have remained practically cut off, thus they have been out of the mere necessity and for the sake of their survival, depending on and making use of their tr aditional unrecorded knowledge†. (Anwar, 1998) Amadou Ba feared that a lot of it is being lost due to rapid urbanization and continuous attrition in the older population. â€Å"Indigenous knowledge is predominantly tacit and embedded in practices and experiences and exchanged within the community through oral communication and demonstration.Recording and disseminating it across communities is not easy† (Anwar. 2005). It’s sometimes fragmented. It does not exist in its totality either in one place or one individual. It is distribution is socially differentiated, based on gender and age. â€Å"When discussing language, ethnic groups, cultures (and subcultures), and religions. The key concepts are diversity and complexity. There are conservatively many hundreds of different ethnics groups. Thus, there are many hundreds of distinct languages and cultures.The sheer number of such groups throughout Africa makes this dimension unique to the continent. † (The Oth er World ch. 6 pg. 187) Amadou Ham pate Ba passed away in 1991, leaving the world a library and an extensive archive to protect the wealth of knowledge that he had collected from fire, which he warned about repeatedly. He said â€Å"that part of every speech is lost to fire; chaos can result from tiny sparks just as a match can lead to a fire that destroys an entire village†. (folkculture. rg) What role do oral traditions play in the displacements and/or migrations of communities? Oral tradition: â€Å"the process of handing down information, opinions, belief, and customs by the word of mouth or by example† (Merriam-Webster unabridged 7th Ed). A transmission of knowledge and institutions through successive generations without written instruction. Thus an inherited principle, standard, or practice serving as the established guide of an individual or group. In comparing different cultures we tend to evaluate the custom of others in light of our own beliefs and values.Mem bers of all cultures assume that their own design for living is the best and only correct way. The belief that one’s own culture is the only true and good way, as well as the tendency to judge other cultures by those standard, is call Ethnocentrism. Ethnocentrism serves several important functions for individuals and groups. Certainly about the rightness of one’s beliefs and behaviors reinforces the tendency to confirm and to defend one’s society. Ethnocentrism becomes dysfunctional when beliefs in one’s superiority lead to hostility and conflict. More important, oral traditions can provide a rich history predating the written word. † (The other world ch6 pg. 189) In traditional soufies people tend to regard the way things have always been done as sacred, which stems from the beliefs and practices passed down from generation to generation. Account of first European contacts with black Africa are a study in Ethnocentrism the letters and journals of 1 5th and 16th century explorers, merchants, and missioners, overflowed with lurid descriptions of cannibalism, incest and unbridled lust. Since the Africans did not practice Christianity they were labeled ‘heathens’; since their laws were incomprehensible to the European, they were said to be ‘LAWLESS’; and since their marriage and family practices differed from those prevalent in Europe they were judged to be ‘savages’ and ‘barbarians’. (George 1968) â€Å"Africa was artificially divided to suit the objectives of the colonial governments. Preexisting ethnic, linguistic, and cultural until were ignored. Throughout Africa, closely knit people speaking the same language were suddenly separated†. The other world Ch6 pg. 190) As evident in the class text book (see enclosed references) European colonization of the coast of Africa in 1884 (see fig 6. 2) undoubtedly hasten the displacement and migration of the indigenous people furt her inland toward the desert (see fig 6. 1) so they could control; the rich fertile land. By 1895 (see fig 6. 3) it only got worse. Even today the African map reflects the extraction goals of the imperial powers. ‘’ Moreover, foreigners exploited the natural habit in many parts of the region.For instance, the colonial powers instituted cash crops and export of livestock, which in turn meant widespread clearing of the land and sometimes depletion of the soil. Similarly, Europeans carving up the continent created or heightened local rivalries, which resulted in conflicts that also affected the landscape (ch6 p. 201) Carried to an extreme, ethnocentrism is destructive as evidence by the Nazis in Germany who believed in absolute superiority of the white Aryan race and culture.The result was the displacement and death of millions of people who didn’t fit that category mostly Jews. In American history, each different ethnic, religious, or racial group was thought to be inferior to white Anglo-Saxon Protestants (WASP) and therefore deserve less than humane treatment. â€Å"Ethnic divisions are a powerful force today. Ongoing struggles in such diverse states as Angola, Burundi, Congo, Ethiopia, Kenya,Liberia Mauritanian, Nigeria, Ruanda and Sierra Leon may be explained in past by deep-seated ethnic division

Airtel Marketing Strategy

Integrated Marketing Communications Group-8, Sec-C Ajit, Anuj, Prateek, Rohit, Vaibhav AIRTEL: Evolution ? ? ? ? Founded: 7th July 1995 First mobile phone company in the world to outsource everything except marketing and sales and finance operates in 20 countries across South Asia, Africa and the Channel Islands The largest cellular service provider in India 4P+2P+3P for AIRTEL ? 4P’s ? Product: Airtel is the fifth largest telecom operator in the world with about 230. 8 million subscribers across 19 countries ? It provides mobile, fixed telephony as well as broadband and subscription television services Airtel won 3G licenses in 13 telecom circles of India ? Product differentiation is limited so main USP is uninterrupted services and troubleshooting support ? ? Price: Price in the telecomm industry are close to similar, hence main focus is on customized payment plans ? User is free to choose between plans which favor cheaper SMS? s or calls ? Pay-per-second of usage v/s Pay-pe r-minute of usage is the latest attraction ? 4P+2P+3P for AIRTEL ? 4P’s ? Promotion: ? Promotions are usually in multiple formats as discussed further in slides Main focus is connectivity, customized plans as well as dependable network ? Place: ? Airtel has separate plans for each of the regions ? Rural customers get more support and focus is on basic services ? Urban customers are main targets for value added services and accordingly Airtel designs its product offerings and communication plans 4P+2P+3P for AIRTEL ? 2P’s ? People: ? Involvement of people with Airtel has increased with campaigns like â€Å"har ek dost zaroori hota hai† ? Final offerings are also highly customized to friend group discounts and so on ? Pack Design: Pack design is kept red to re-inforce Airtel Brand ? Description of Plans is also evident 4P+2P+3P for AIRTEL ? 3P’s ? Peer -to-peer: ? High rate of communication to increase peer-to-peer interaction and reviews especially in rece nt stages ? Personalization: ? Personalization is constantly on rise especially with value- added-services ? Participation: ? Airtel has tried to conduct contest every now and then to maximize customer participation but due to high brand clutter it is difficult Media Vehicles ? ? ? ? ? ? Above the line Advertising ? Television ? Radio Print Media ? Out-of-home ? Cinema Below the line Advertising ? Trade Scheme ? Consumer offer ? In-shop and shop-front activities Direct Marketing Events Buzz Digital Communication Ad Agencies ? Creative Agency- JWT India ? ? ? ? Airtel ended its 15-year-long relationship with creative agency, Rediffusion – Y&R on Aug, 2010. Rediffusion has handled the brand since its inception in 1995 The Airtel account is worth Rs 400 crore in terms of ad spends This also led to change in their logo Madison Media handles ? ? The media duties for Airtel for more than five years nowIt also handles out-of-home and digital for the brand too Airtel TV Commercials T V Ad Campaigns by Airtel ? â€Å"Har ek friend zaroori hota hai† ? Purpose: ? The commercial for Airtel aims to make the brand trendier for the youth, while attempting not to alienate its older target audience set ? To position Airtel as a brand that embodies friendship, and helps all sorts of friends connect with one another ? TV Advertisement analysis: ? The commercial depicts different kinds of friends one has, and how the presence of each one is necessary in some way or the other ?A jingle penned by film lyricist Amitabh Bhattacharya, makes use of ‘Hinglish' and popular youth lingo, and has the story of different categories of friends, such as the one who wakes one up during the wee hours for help, or another who may give you company during your financial crunch days ? The jingle ends with ‘Har ek friend zaroori hota hai', and with the message that Airtel keeps one connected to their friends TV Ad campaigns by Airtel ? ? ? ? ? ? ? â€Å"Dil jo chaahe paas laa ye† â€Å"Baat karne se hi baat banti hai† â€Å"Do airtel bajenge to tarakki main char chand lag jaenge† â€Å"Dil jo chahe pass laye† Kuch bandhan atoot hote hain, jaise Airtel ka network† â€Å"Airtel internet 3G par† â€Å"Express yourself † †Har ek friend zaroori hota hai† Ad â€Å"Do airtel bajenge to tarakki main char chand lag jaengeâ€Å" Ad â€Å"Dil jo chahe pass laye† Ad ATL-TV ? ? ? It creates Pervasiveness, allows Airtel to be in the eyes of the audience all the time Even though the audience is not obligated to pay heed to the advertisements, the high creativity quotient of the Airtel Ads makes it virtually impossible for the audience to turn a blind eye to them The Ads are very high on the use of imagery and music ATL-TV ? ? ? The genius of the Oscar winning music director A.R. Rahman is the man behind the catchy tune Airtel advertises more on its brand and its values than its products and services Mo st ads just establish the value and beliefs of Airtel than establishing its services like mobile, telephone, or broadband ATL-TV ? ? The likes of Sachin Tendulkar, Shah Rukh Khan, Saif Ali Khan, Kareena Kapoor, Vidya Balan, A R Rahman have all been brand ambassadors of Airtel at some point or the other One of the key reasons for the lasting impact of the Airtel ads is the reinvention of the content displayed TV (Sponsorship) ? ? Leading sponsor of Kaun Banega Crorepati Airtel subscribers were given a special chance to directly enter KBC ? Participation to the show was only restricted to the Airtel subscribers and BSNL/MTNL landline users for the first couple of seasons. Sponsor of Indian Idol ? Airtel subscribers got an exclusive chance to enter the show TV (Sponsorship) ? ? BCCI has awarded the series sponsorship rights of all international cricket matches played in India to Bharti Airtel for the period 2010-2013 On 9 May 2009, Airtel signed a major deal with Manchester United Foot ball Club TV (Sponsorship) ? ? In 2009, Airtel had signed a three-year deal orth Rs 150 crore with official tournament broadcaster ESPN Star Sports for the title sponsorship of the T20 league. Airtel signed a deal to be title sponsor the inaugural Formula One Indian Grand Prix during the 2011 season Print Media Radio ? Bharti Airtel is among the top two advertiser on radio in India (1% share) ? Promotional ads released by Airtel on radio: ? ? ? ? ? ? ? ? Mobile recharge Score kya hua? Aaj ka kya plan hai? EMI Airtel World Cup Pack Airtel happy Recharge Airtel Minimum Recharge Marathon Airtel – radio ad jingle Consumer Sales Promotions ? ? ? ? ? â€Å"Friendz† pre-paid plan for youth Ladies Special† plan â€Å"Seniors plan† for discounts to senior citizens Executive Corporate Plans â€Å"Family Celebrations offer† – Special discounts in Call rates & SMS services Promotional Campaigns ? ? ? ? ? ? ? Airtel Jai Hind AD Campaign Leadership campaig n Quality Time Campaign Magic Dalo Say Hello Launch campaign Magic Hai to Mumkin Hai campaign Call Karo Sona Jeeto campaign Promotions: Health Campaigns ? ? ? ? Airtel and Wockhardt hospitals together launched a â€Å"Good Health† campaign to mark World Health Day on April 7 Comprised two health check-ups at discount of 75% Post-paid subscribers of Airtel could avail theWockhardt master health check up at Rs 799 against a original cost of Rs 3200 Also available as part of the campaign was the Wockhardt Heart Check at Rs 499, aginst Rs 2400 Grameen Mobile Puratchi: Rural Markets ? ? ? This scheme was for more than 45 lakh society members of IKSCL (IFFCO Kisan Sanchar Coopreative ltd) Farmers had five free Value Added Services under this scheme. The farmers had five free voice messages on mandi prices, farming techniques, weather forecasts, dairy farming, animal husbandry, rural health initiatives on a daily basis The pack for farmers ranged between Rs 1299 andRs 4000 along wit h the mobile phone. Direct Marketing ? Direct marketing techniques used: ? Email Marketing ? Display Ads, Social Media sites ? Location based marketing tools, QR Codes ? Telemarketing to customers Events (1/2) ? To reach their target audiences, Airtel has sponsored various TV programmes like ? Big Boss ? Indian Idol ? Super Singer ? Indian Sangeet awards ? Bol Baby Bol Events (2/2) ? Airtel has sponsored various events like ? Indian Grand Prix 2011 ? Champions League T20 ? Delhi Half Marathon ? Border-Gavaskar Trophy, other cricket tours ? Indian Fantasy League ? Indian Golf festival Buzz ? ? ?Launch of Blackberry, tie up with RIM Indian Grand Prix 2011 Social Networking sites ? Facebook, ? Twitter Airtel Simulator Challenge Airtel Out of Home Advertising – Hoardings ? ? ? ? Launching 360 degree campaign, spread over 43 days, rolled out in metros, mini metros in association with Madison media plus group Want to make the brand the part of every day life of costumer. Depict Air tel as youthful, vibrant &dynamic brand Gantries, bus shelters pole, neon's, traffic timers, unipoles, dropdowns, public utility branding, station branding etc are the form of advertisements involved Airtel Out of Home Advertising – Transit Medium,Street Furniture ? ? ? ? To communicate from door to door Seek more attention of the customer Key nodal points of market and high traffic points, TG dwelling and the concentration area Sky ballon branding, boat branding, Cycle branding, Airtel Product Placement Months before the announcement of the August 22nd iPhone launch, fanatics in India were screaming for their shot at iPhone 3G mania. You would think from the crowds in the photo that the Airtel iPhone launch in Mumbai, India was a raging success. Think again! One cult of iPhone follower present at Airtel's testical festival knows otherwise.Airtel Branded Entertainment ? ? ? Way to create buzz The ads can be flashed in between the various highly watched TV serials or can be sp onsors of some big movies Cricket matches, Super star awards, Dance, singing competitions Airtel Sensory Branding ? Through its signature tune ? Its unique color and logo ? Having celebrities like Sachin Tendulkar and A. R. Rahman Digital Communication: Web 2. 0 Digital Communication: Web 2. 0 Digital Communication: Web 2. 0 Digital Communication: Web 2. 0 CSR Initiatives ? ? ? Initiative of opening â€Å"Airtel Ashiana† for underprivileged children at the Mohali office of AirtelTied up with an NGO to distribute daily surplus food to needy children â€Å"Airtel Experience Centre by Access MO† for the benefit of visually impaired people as well as people from deprived section of society CSR Initiatives ? ? Bharti foundation, the philanthropic arm of Bharti Enterprises was established in 2000 with a vision to help underprivileged children and young people of our country realise their potential In the process of setting up a 1000 â€Å"Satya Bharti Schools† to deli ver high quality education to underprivileged children in the deepest rural pockets The First Mover Advantage 1.Electronic recharge 2. Hello Tunes 3. Airtel Live! 4. Portfolio Manager 5. Song Catcher 6. Easy Music 7. Black berry handsets 8. M-cheques Airtel- Retail Media ? ? ? ? Presence of recharging options through an extensive network of small stores/big retail stores/small or big retail shops/pan shops etc Easy way to recharge option by keeping a specific number digit for a particular type of recharge option Availability of new sim cards free of cost to increase the customer base at various outlets Airtel owned stores and Airtel galleries present in every district to address customer queries more responsiblySocial, Ethical & Legal Issues ? ? VAS Fraud ? There has been lot of criticism about Airtel for its unauthorized VAS activation ? Many of its services were activated automatically according to a complaint ? Several thousands of users were falsely billed ? In return Airtel lau nched STOP/START 121 services for such issues ? Alternatively, one can sign up on the â€Å"Do Not Disturb† list to avoid all telemarketing calls and SMS Controversy ? Bharti Airtel(India) was issued notices by Telecom Regulatory Authority of India(TRAI) for violation of Mobile number portability(MNP) Regulations. According to TRAI, it had received complains from customers regarding wrong rejection of porting requests by telecom operators Social, Ethical & Legal Issues ? ? Silcon Concept has dragged Airtel to the Federal High Court over allegedly making a publication to the claimant? s customers and subscriber by means of voice call, text messages or SMS informing them that the claimant is a band of fraudster (Oct, 2010) The CCC of ASCI has concluded that Airtel? s advertisement (campaign ‘Dil Titli„) is misleading, as the viewer of the TV commercial is led to believe that Airtel Digital TV has superior picture uality because of MPEG4 or DVBS2 technology (Jan, 201 0) ‘Dil Titli‘campaign Social, Ethical & Legal Issues ? ? ? The AIRTEL Digital TV advertisement offering ‘Free Regional Pack for life„ was accused of being misleading as the DTH licence was valid only up to May 2018 (Feb, 2010) The CCC of ASCI found the claim made in the SMS ad that Airtel Digital TV Recorder is High Definition capable as misleading BSNL has accused Airtel of unfair trade practices over the private operator's claim that it is the only mobile telecom service provider in Jammu & Kashmir (J&K) (Dec, 2004) Thank You